Metrics details. The three primary headaches, tension-type headache, migraine and cluster headache, occur in both genders, but all seem to have a sex-specific prevalence. These gender differences suggest that both male and female sex hormones could have an influence on the course of primary headaches. This review aims to summarise the most relevant and recent literature on this topic. The estrogen withdrawal hypothesis forms the basis for most of the assumptions made on this behalf. The role of other hormones as well as the importance of sex hormones in other primary headaches is far less studied. The available literature mainly covers the role of sex hormones in migraine in women.
Gain-of-function mutations of fem-3, a sex-determination gene in Caenorhabditis elegans
Systems used to automatically annotate proteins with high accuracy:. Select item s and click on "Add to basket" to create your own collection here entries max. Manual assertion based on experiment in i. Component of a complex containing fem-1, fem-2 and fem-3 PubMed: Part of a E3 ubiquitin-protein ligase complex, at least composed of cul-2, elc-1, tra-1, fem-1, fem-2 and fem-3; mediates the ubiquitination and subsequent proteasomal degradation of tra-1 PubMed:
A more recent article on sexual dysfunction in women is available. See related patient information handout on sexual dysfunction in women , written by the author of this article. Related Editorial. Sexual dysfunction includes desire, arousal, orgasmic and sex pain disorders dyspareunia and vaginismus.
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